Thursday, 7 February 2019

Collagen: Building Nature’s Infrastructure

Global Journal of Nutrition & Food Science 



Collagen has been a personal passion of mine since graduate school where my thesis tells the story of how collagen and elastin cross-links are affected by d-penicillamine, a remarkable amino acid. Collagen has been around since metazoan times. Its structure is elegantly simple and simply elegant. Glycine-proline-Any amino acid is a base unit that, when repeated about 1,000 times, becomes one strand of collagen. Three strands wind together to make a single collagen molecule. Collagen is a major part of the infrastructure of all mammals, fish, birds, and crustacean. The infrastructure includes bones and joints, arteries and veins, tendons and fascia. The orienting basement membrane that every cell receives nourishment from and exports metabolic products and wastes has a specialized collagen core.


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